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The vaccine, developed by researchers at the University of Western Ontario, has been approved by the U.S. Food and Drug Administration to start being tested in humans in January.
It is the first preventive HIV vaccine approved for clinical trials to use a whole HIV-1 virus, which has been both killed and genetically engineered, to activate immunity. In this way, the new vaccine is much like the killed whole virus vaccines that are successful against polio, rabies and influenza.